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Schematic drawing showing the experimental design. Adeno-associated viral vectors (AAVs) were injected into two sites (red arrows) at the ischemic penumbra 1 hour after middle cerebral artery occlusion (MCAO). Dark blue highlights the infarct area and light blue highlights the penumbra. Brain samples were collected 3 weeks after vector injection. The squares show the regions used for histological analysis. The color reproduction of this figure is available at online version.
