Table 1. Clinical and microbiological features of pulmonary infection with Mycobacterium triplexa.
Characteristic | Patient described in reference 15 | Patient described in reference 16 | Our patient |
---|---|---|---|
Age/Sex | 67/F | 54/F | 54/F |
Symptoms | Hemoptysis | Cough, hemoptysis, fever, fatigue | Cough, fatigue |
Findings | Bronchiectases, lung nodules | Lung infiltrates and nodule (0.3 cm) | Bronchiectases, lung nodules, cavitations |
Collected samples (no.) | Bronchial aspirate (1), sputum (3) | BAL (2), sputum (4) | Bronchial aspirate (7), BAL (2) |
Smear-positive | None | None | 6 |
Culture-positive | 3 | 3 | 9 |
Mean no. CFU/mL (range) | NR | NR | 693 (144–2,772) |
In vitro testing | |||
S | RMP, SM, CLA | NR | CLA |
I | CIP | NR | AN, CIP, EMB, ETH, RBT, SM |
R | EMB, INH, PZA | NR | INH, RMP |
Therapeutic schedule (mo.) | RMP, CIP, EMB, CLA (18) | RMP, INH, CLA (NR) | INH, RMP, EMB (6); EMB, CLA (9); LVX, CLA, EMB (9) |
Outcome | Healed | NR | Slight improvement |
aBAL, bronchoalveolar lavage; NR, not reported; S, susceptible; I, moderately susceptible; R, resistant; RMP, rifampin; SM, streptomycin; CLA, clarithromycin; CIP, ciprofloxacin; AN, amikacin; EMB, ethambutol; ETH, ethionamide; RBT, rifabutin; INH, isoniazid; PZA, pyrazinamide; LVX, levofloxacin.