Table 1. Distribution of rs6971 genotypes against ligand binding classification.
TSPO genotype |
Binding phenotype (subject, n) |
|||
---|---|---|---|---|
DNA (polymorphism rs6971) | Protein (position 147) | HAB | MAB | LAB |
C/C | Ala/Ala | 27 | ||
C/T | Ala/Thr | 12 | ||
T/T | Thr/Thr | 2 |
Ala=alanine, Thr=threonine, HAB=high affinity binder, MAB=mixed affinity binder, LAB=low affinity binder.
Genotypes correspond to carriage of the 147 amino acid as follows: CC=Ala147/Ala147; CT=Ala147/Thr147; TT=Thr147/Thr147.