Table 1. Comparison of intrasubtype/CRFa genetic distances and subtype distribution.
Subtype/CRF | Kinshasa: mid-1980s |
DRC: 1997 |
||||
---|---|---|---|---|---|---|
n | Nucleotide distance (%) | % frequency of subtype | n | Nucleotide distance (%) | % frequency of subtype | |
A | 22 | 15.1 | 44 | 84 | 20.8b | 46 |
C | 3 | 13.1 | 6 | 18 | 18.0b | 10 |
D | 10 | 12.1 | 20 | 23 | 18.7b | 13 |
CRF01-AE | 3 | 9.6 | 6 | 4 | 17.9b | 2 |
G | 5 | 15.6 | 10 | 15 | 20.1b | 8 |
F1 | 3 | 10.0 | 6 | 7 | 14.8b | 4 |
H | 2 | 18.7 | 4 | 16 | 23.5 | 9 |
J | 1 | – | 2 | 7 | 21.2 | 4 |
K | 1 | – | 2 | 7 | 20.4 | 4 |
aCRF, circulating recombinant forms; DRC, Democratic Republic of Congo. bSignificant difference (distances significance test = t test, frequency of subtypes significance test = Fisher exact test).