Table 2.
Treatment of COPD exacerbations in general practice
| Case 1 | Case 2 | Case 3 | Case 4 | |||||
|---|---|---|---|---|---|---|---|---|
| GOLD 1,2 no severe exacerbation | GOLD 1,2 no severe exacerbation | GOLD 3,4 severe exacerbation | GOLD 3,4 severe exacerbation | |||||
| DM- [CI] | DM+ [CI] | DM- [CI] | DM+ [CI] | DM- [CI] | DM+ [CI] | DM- [CI] | DM+ [CI] | |
| Choice of treatment | N = 165 | N = 161 | N = 164 | N = 159 | N = 166 | N = 158 | N = 158 | N = 156 |
| 1- Specialist treatment | 0% [0.000-0.000] |
0% [0.000-0.000] |
10% [0.057-0.154] |
16% [0.104-0.223] |
0% [0.000-0.000] |
0% [0.000-0.000] |
61% [0.527-0.684] |
72% [0.640-0.787] |
| 2- No treatment | 2% [0.004-0.052] |
5% [0.022-0.096] |
0% [0.000-0.000] |
0% [0.000-0.000] |
0% [0.000-0.000] |
1% [0.002-0.045] |
0% [0.000-0.000] |
0% [0.000-0.000] |
| 3- Primary care treatment | 98% [0.948-0.996] |
95% [0.904-0.978] |
90% [0.846-0.943] |
84% [0.777-0.896] |
100% [0.967-1.000] |
99% [0.955-0.998] |
39% [0.316-0.473] |
28% [0.213-0.360] |
| Type of regimen | N = 162 | N = 157 | N = 147 | N = 134 | N = 166 | N = 157 | N = 62 | N = 43 |
| A) Tapering regimen | 0% [0.000-0.000] |
3% [0.010-0.073] |
1% [0.000-0.037] |
3% [0.008-0.075] |
2% [0.004-0.052] |
6% [0.027-0.106] |
6% [0.018-0.157] |
9% [0.026-0.221] |
| B) Continuous regimen | 100% [0.966-1.000] |
97% [0.927-0.990] |
99% [0.963-1.000] |
97% [0.925-0.992] |
98% [0.948-0.996] |
94% [0.894-0.973] |
94% [0.843-0.982] |
91% [0.779-0.974] |
| Continuous regimen | N = 161 | N = 149 | N = 143 | N = 128 | N = 160 | N = 141 | N = 57 | N = 38 |
| 30mg for 5 days | 13% [0.083-0.192] |
17% [0.112-0.238] |
5% [0.020-0.098] |
6% [0.027-0.119] |
8% [0.044-0.135] |
9% [0.050-0.153] |
2% [0.000-0.094] |
5% [0.006-0.177] |
| 30mg for 7 days | 64% [0.560-0.714] |
57% [0.487-0.651] |
57% [0.488-0.656] |
61% [0.519-0.694] |
58% [0.501-0.659] |
59% [0.503-0.671] |
44% [0.307-0.576] |
42% [0.263-0.592] |
| 30mg for 10 days | 8% [0.044-0.134] |
6% [0.028-0.112] |
22% [0.152-0.293] |
20% [0.137-0.283] |
22% [0.157-0.291] |
20% [0.136-0.274] |
42% [0.291-0.559] |
40% [0.240-0.566] |
| 30mg for 14 days | 0% [0.000-0.000] |
0% [0.000-0.000] |
4% [0.016-0.089] |
1% [0.000-0.043] |
4% [0.014-0.080] |
1% [0.000-0.039] |
5% [0.011-0.146] |
5% [0.006-0.177] |
DM - = patients without diabetes; DM + = patients with diabetes; CI = 95% confidence interval