Table 1. General characteristics of study participants.
| Full Sample (n = 57) | APOE ε3/ε3 carriers (n = 29) | APOE ε4 carriers (n = 28) | p | |
| Age, years (SD) | 61.6 (8.2) | 62.1 (8.5) | 61.1 (8.1) | 0.664 |
| Gender, male/female (% male) | 21/36 (37) | 11/18 (38) | 10/18 (36) | 0.862 |
| Education, years (SD) | 10.4 (3.4) | 10.2 (3.3) | 10.6 (3.5) | 0.631 |
| BMI, kg/m2 (SD) | 26.1 (3.2) | 26.2 (3.2) | 25.9 (3.3) | 0.718 |
| Smokers, n (%) | 13 (23) | 6 (21) | 7 (25) | 0.698 |
| Systolic blood pressure, mmHg (SD) | 143.2 (16.9) | 143.6 (15.2) | 142.7 (18.8) | 0.835 |
| Diastolic blood pressure, mmHg (SD) | 82.4 (9.3) | 82.9 (9.5) | 81.9 (9.2) | 0.667 |
| Hypertension, n (%)a | 34 (60) | 18 (62) | 16 (57) | 0.705 |
| Heart disease, n (%) | 11 (19) | 6 (21) | 5 (18) | 0.786 |
| Diabetes (type 2), n (%) | 2 (4) | 1 (3) | 1 (4) | 0.980 |
| Prescription drugs (SD) | 1.2 (1.4) | 1.1 (1.3) | 1.3 (1.5) | 0.702 |
| MMSE score (SD) | 28.1 (1.6) | 27.9 (1.8) | 28.2 (1.5) | 0.571 |
| Left hippocampus volume, mm3 (SD)b | 2757 (284) | 2750 (274) | 2757 (288) | 0.931 |
| Right hippocampus volume, mm3 (SD)b | 2895 (356) | 2959 (371) | 2827 (333) | 0.162 |
| Total hippocampus volume, mm3 (SD)b | 5652 (565) | 5709 (587) | 5583 (537) | 0.403 |
| Leukocyte telomere length, bp (SD)c | 5573 (644) | 5401 (537) | 5752 (705) | 0.039 |
All values are means unless otherwise stated. MMSE, Mini-mental state examination; SD, standard deviation.
a
Blood pressure ≥140/90 or taking antihypertensive medication.
b
Adjusted for body (and head) size and age.
c
Adjusted for age.