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. 2012 Apr 10;7(4):e33660. doi: 10.1371/journal.pone.0033660

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Shaw et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The volume of the cerebellum is expressed as a percentage of the caudal cranial fossa volume (Panels A and B: Cerebellar CCF Percentage) and a percentage of the total brain volume (Panels C and D: Cerebellar Brain Percentage). Cavalier King Charles Spaniels (CKCS) have a relatively larger cerebellum than small breed dogs and Labradors (Panels A and C). CKCS under 2 years of age with Chiari-like malformation (CM) and syringomyelia (SM) (CKCS CM/SM) have a relatively larger cerebellum than CKCS over 5 years of age with CM but without SM (CKCS CM, Panels B and D). *p<0.05, **p<0.01, ***p<0.001.