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. 2012 Apr 10;7(4):e35022. doi: 10.1371/journal.pone.0035022

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Ai et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A)–(C) are representative view of 786-O cell line transfected with Notch1, Jagged1 and control plasmid respectively. (D)–(F) are Caki-1 cell line transfected with Notch1, Jagged1 and control plasmid respectively. (G) Notch1 and Jagged1 can promote the migration of 786-O and Caki-1 tumor cell lines compared to the controls. (H) MMP-9 mRNA expression was significantly elevated in Caki-1 and 786-O cell lines after transfected with Notch1 and Jagged1 plasmid. The data shown are mean±SD.