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. 2012 Apr 10;7(4):e35240. doi: 10.1371/journal.pone.0035240

Figure 3. Effects of orally administered fatty acids on incretins and other hormones.

Figure 3

(A-F) Three-month-old lean C57BL/6N mice were fasted overnight and orally dosed with saline, sodium butyrate, sodium propionate, sodium acetate, an SCFA admixture (65% sodium acetate, 20% sodium propionate, 15% sodium butyrate), octanoic acid (OA), or α-linolenic acid (LA), all at 400mg/kg body weight. Plasma levels of total GLP-1, active GLP-1, GIP, PYY, insulin, and amylin were measured 10 minutes after dosing. Intra-assay CV% was below 8.9% for all immunoassays. Data are mean ± SEM. N=8. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001 vs. saline. NS: not significant.