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. 2012 Apr 10;7(4):e35240. doi: 10.1371/journal.pone.0035240

Figure 4. Effects of butyrate and propionate on energy homeostasis in Ffar3 knockout mice.

Figure 4

(A) Body weight of three-month-old Ffar3 knockouts and wild-type littermates on standard chow diet and one week after switching to HFD. N=34–41. (B-D) After one week of HFD feeding, Ffar3 knockouts and wild-type littermates were switched to HFD containing sodium butyrate (5%) or sodium propionate (4.3%) for eight days. Cumulative body weight change and daily food intake are shown. Data are mean ± SEM. N=8–13. *P<0.05, **P<0.01, ***P<0.001 vs. control diet. #P<0.05 vs. wild-type mice on control diet. NS: not significant.