Table 3.

Comparison of ratings of reasons against and reasons for participation between enrollees and decliners.^a

Reasons	Enrollees N=61	Decliners N=10	pb
Reasons against participation
It seems too dangerous	2.0 (0.8)	3.7 (0.6)	<.001
I don’t like the idea of brain surgery	2.5 (0.7)	3.4 (1.0)	.003
I don’t want to be a guinea pig	1.6 (0.7)	2.5 (1.1)	.02
The purpose of the study was not solely to benefit me directly	1.1 (0.3)	1.2 (0.4)	.46
It seems like a lot of work for me to be involved in this kind of study	1.3 (0.5)	1.9 (0.9)	.02
Reasons in favor of participation
I hope it will help my PD	3.8 (0.4)	3.9 (0.3)	.66
I would be helping other patients with PD	3.1 (0.8)	3.2 (0.9)	.86
It’s better to do something rather than just waiting for my PD to get worse	3.9 (0.3)	3.0 (0.9)	<.001
Maybe it might help me in the long run, if the research succeeds	3.0 (0.8)	2.4 (1.0)	.08
I want to contribute to science	2.9 (0.9)	2.7 (0.9)	.47
I expect it will help my PD	2.5 (1.1)	1.8 (0.9)	.04
I need to try this for the sake of my loved ones	2.8 (1.0)	2.1 (1.1)	.05

^aValues are expressed as mean (SD); range of scores, 1=not a reason, 2=minor reason, 3=moderate reason, 4=strong reason.

^bMann-Whitney test.