Table 2.
Model 1: unadjusted |
Model 2: adjusted for sex, paternal social class |
Model 2 + adult social class |
Model 2 + educational attainment |
Model 2 + depression |
Adjusted for all covariables |
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OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | |
1946 cohort | ||||||||||||
Cognition | 0.66 (0.53 to 0.82) | <0.001 | 0.70 (0.56 to 0.86) | 0.001 | 0.78 (0.63 to 0.98) | 0.04 | 0.80 (0.63 to 1.02) | 0.07 | 0.69 (0.56 to 0.86) | 0.001 | 0.84 (0.66 to 1.07) | 0.15 |
Quartile 1 (least able) | 1 | 1 | 1 | 1 | 1 | 1 | ||||||
Quartile 2 | 0.77 (0.46 to 1.29) | 0.32 | 0.84 (0.50 to 1.42) | 0.52 | 0.98 (0.57 to 1.67) | 0.93 | 0.95 (0.56 to 1.61) | 0.84 | 0.84 (0.50 to 1.41) | 0.51 | 1.02 (0.60 to 1.74) | 0.94 |
Quartile 3 | 0.49 (0.27 to 0.88) | 0.02 | 0.54 (0.30 to 0.96) | 0.04 | 0.65 (0.36 to 1.19) | 0.17 | 0.67 (0.36 to 1.24) | 0.21 | 0.52 (0.29 to 0.95) | 0.03 | 0.71 (0.38 to 1.33) | 0.29 |
Quartile 4 (most able) | 0.26 (0.11 to 0.58) | 0.001 | 0.31 (0.13 to 0.70) | 0.005 | 0.44 (0.18 to 1.05) | 0.06 | 0.45 (0.18 to 1.11) | 0.09 | 0.30 (0.13 to 0.69) | 0.005 | 0.53 (0.21 to 1.33) | 0.17 |
1958 cohort | ||||||||||||
Cognition | 0.68 (0.60 to 0.76) | <0.001 | 0.69 (0.61 to 0.77) | <0.001 | 0.69 (0.61 to 0.78) | <0.001 | 0.77 (0.67 to 0.90) | 0.001 | 0.72 (0.64 to 0.81) | <0.001 | 0.79 (0.68 to 0.92) | 0.002 |
Quartile 1 (least able) | 1 | 1 | 1 | 1 | 1 | 1 | ||||||
Quartile 2 | 0.67 (0.51 to 0.88) | 0.004 | 0.68 (0.52 to 0.89) | 0.005 | 0.68 (0.52 to 0.90) | 0.006 | 0.78 (0.59 to 1.03) | 0.09 | 0.72 (0.54 to 0.94) | 0.02 | 0.81 (0.61 to 1.07) | 0.13 |
Quartile 3 | 0.43 (0.31 to 0.59) | <0.001 | 0.44 (0.32 to 0.61) | <0.001 | 0.45 (0.33 to 0.62) | <0.001 | 0.56 (0.40 to 0.79) | 0.001 | 0.49 (0.35 to 0.68) | <0.001 | 0.60 (0.42 to 0.84) | 0.003 |
Quartile 4 (most able) | 0.32 (0.22 to 0.48) | <0.001 | 0.35 (0.24 to 0.52) | <0.001 | 0.36 (0.24 to 0.54) | <0.001 | 0.49 (0.30 to 0.81) | 0.005 | 0.39 (0.26 to 0.59) | <0.001 | 0.53 (0.32 to 0.86) | 0.01 |
1970 cohort | ||||||||||||
Cognition | 0.78 (0.64 to 0.94) | 0.01 | 0.80 (0.66 to 0.97) | 0.03 | 0.84 (0.69 to 1.03) | 0.1 | 0.85 (0.70 to 1.02) | 0.08 | 0.80 (0.66 to 0.98) | 0.03 | 0.87 (0.72 to 1.05) | 0.15 |
Quartile 1 (least able | 1 | 1 | 1 | 1 | 1 | 1 | ||||||
Quartile 2 | 0.94 (0.48 to 1.82) | 0.85 | 0.97 (0.50 to 1.88) | 0.93 | 1.03 (0.52 to 2.03) | 0.93 | 1.0 (0.51 to 1.94) | 0.99 | 0.97 (0.50 to 1.87) | 0.92 | 1.03 (0.52 to 2.02) | 0.93 |
Quartile 3 | 0.71 (0.44 to 1.15) | 0.17 | 0.74 (0.46 to 1.21) | 0.24 | 0.82 (0.50 to 1.34) | 0.43 | 0.80 (0.50 to 1.29) | 0.37 | 0.75 (0.46 to 1.22) | 0.24 | 0.82 (0.50 to 1.34) | 0.43 |
Quartile 4 (most able) | 0.44 (0.21 to 0.90) | 0.03 | 0.48 (0.24 to 0.98) | 0.04 | 0.56 (0.26 to 1.19) | 0.13 | 0.57 (0.28 to 1.12) | 0.10 | 0.48 (0.24 to 0.98) | 0.04 | 0.56 (0.26 to 1.19) | 0.13 |