Table 3.
Thirty-day mortality (in per cent) in patients with an IBD diagnosis undergoing total colectomy in the period 1996–2010 in Denmark, by emergency versus elective surgery
| Ulcerative colitis |
Crohn's disease |
Ulcerative colitis and Crohn's disease* |
||||
| Emergency | Elective | Emergency | Elective | Emergency | Elective | |
| All | 5.2 (55/1056) | 0.9 (8/938) | 8.1 (11/136) | 1.5 (3/201) | 4.0 (10/247) | 1.0 (3/311) |
| Males | 5.8 (31/559) | 0.8 (4/485) | 6.5 (4/62) | 2.6 (2/76) | 2.7 (3/113) | 0.7 (1/137) |
| Females | 5.2 (24/497) | 0.9 (4/453) | 9.5 (7/74) | 0.8 (1/125) | 5.2 (7/134) | 1.1 (2/174) |
| Age at operation | ||||||
| 0–39 years | 0.2 (1/503) | 0.2 (1/436) | 0 (0/56) | 0 (0/121) | 0 (0/134) | 0 (0/161) |
| 40–59 years | 1.7 (5/286) | 0.0 (0/292) | 5.1 (2/39) | 0 (0/55) | 3.1 (2/65) | 1.1 (1/91) |
| ≥60 years | 18.4 (49/267) | 3.3 (7/210) | 22.0 (9/41) | 12 (3/25) | 16.7 (8/48) | 3.4 (2/59) |
| Number of annual colectomies for IBD performed by the surgical department | ||||||
| ≤3/year | 11.3 (19/168) | 1.5 (2/131) | 22.6 (7/31) | 4.5 (1/22) | 4.7 (2/43) | 0 (0/45) |
| 3–12/year | 5.9 (11/186) | 1.8 (3/166) | 8.3 (2/24) | 0 (0/28) | 4.0 (2/50) | 0 (0/44) |
| >12/year | 3.6 (25/702) | 0.5 (3/641) | 2.5 (2/81) | 1.3 (2/151) | 3.9 (6/154) | 1.4 (3/222) |
| Duration of hospitalisation before colectomy | ||||||
| Admitted <8 days before colectomy | 7.1 (21/296) | 0.2 (1/557) | 20.0 (9/45) | 1.5 (2/136) | 4.7 (4/85) | 0.0 (0/178) |
| Admitted ≥8 days before colectomy | 4.5 (34/760) | 1.8 (7/381) | 2.2 (2/91) | 1.5 (1/65) | 3.7 (6/162) | 2.3 (3/133) |
| Medical treatment within 1 year before colectomy | ||||||
| TNF-α or cyclosporine | 0 (0/67) | 0 (0/64) | 0 (0/12) | 0 (0/10) | 0 (0/23) | 0 (0/37) |
| Reoperation within 30 days postoperatively | 8.8 (9/102) | 4.1 (3/73) | 18.1 (2/11) | 4.8 (1/21) | 7.4 (2/27) | 0 (0/21) |
| Charlson Comorbidity Index Score | ||||||
| 0 | 2.2 (18/810) | 0.6 (4/705) | 3.1 (3/96) | 0.0 (0/146) | 2.1 (4/191) | 0.9 (2/224) |
| 1–2 | 12.9 (25/194) | 1.6 (3/194) | 20.0 (6/30) | 4.4 (2/45) | 6.1 (3/49) | 1.4 (1/69) |
| ≥3 | 23.1 (12/52) | 2.6 (1/39) | 20.0 (2/10) | 10 (1/10) | 42.9 (3/7) | 0 (0/18) |
| Colectomy type | ||||||
| Colectomy with ileorectal anastomosis (KJFH00—01) | 15.8 (6/38) | 0 (0/54) | 6.3 (1/16) | 0 (0/42) | 0 (0/19) | 0 (0/39) |
| Colectomy with ileostomy (KJFH10—11) | 4.9 (43/875) | 1.5 (8/523) | 9.3 (9/97) | 3.0 (3/99) | 4.6 (9/196) | 1.2 (2/170) |
| Proctocolectomy with ileostomy (KJFH20—21) | 5.5 (4/73) | 0 (0/147) | 0 (0/8) | 0 (0/49) | 0 (0/21) | 0 (0/65) |
| Restorative proctocolectomy ± ileostomy (KJFH30—33) | 6.5 (2/31) | 0 (0/197) | 0 (0/2) | 0 (0/5) | 0 (0/4) | 3.6 (1/28) |
| Proctocolectomy with Koch reservoir (KJFH40) | 0 (0/1) | 0 (0/1) | 0 (0/0) | 0 (0/5) | 0 (0/0) | 0 (0/0) |
| Other form of colectomy (KJFH96) | 0 (0/38) | 0 (0/16) | 7.7 (1/13) | 0 (0/6) | 14.3 (1/7) | 0 (0/9) |
| Time period | ||||||
| 1996–2000 | 5.9 (22/371) | 0.3 (1/307) | 7.4 (4/54) | 1.5 (1/67) | 1.1 (1/90) | 0.9 (1/114) |
| 2001–2005 | 5.2 (20/385) | 0.3 (1/343) | 2.8 (1/36) | 2.6 (2/78) | 6.0 (5/84) | 1.1 (1/95) |
| 2005–2010 | 4.3 (13/300) | 2.1 (6/288) | 13.0 (6/46) | 0 (0/56) | 5.5 (4/73) | 1.0 (1/102) |
*
Patients for whom codes for both ulcerative colitis and Crohn's disease were used at any preceding or subsequent admission or hospital contact.
IBD, inflammatory bowel disease; TNF, tumour necrosis factor.