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. 2012 Mar;14(3):169–177. doi: 10.1593/neo.12414

Figure 1.

Figure 1

18F-BO and FL-BO. (A) Binding model depicting 18F-BO and PARP-1, with the 2H-phthalazin-1-one binding to the catalytically active site on PARP-1. (B) IC50 curves and values for 18F-BO (from Keliher et al. [8]) and FL-BO.