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. 2012 Apr 1;5(2):66–71. doi: 10.1593/tlo.11307

Table 2.

Direct and Indirect NO-Based Radiosensitization Strategies

Direct Indirect
Hypoxia-activated NO donors
  • SNAP and GSNO

  • RRx-001 (ABDNAZ)

NO response manipulation strategies
  • Thrombospondin-1/CD-47 modulation

Indirect activation of endogenous NOS
  • Insulin and electrical stimulus

  • Lipid A analog, ONO-4007