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. Author manuscript; available in PMC: 2012 Nov 24.
Published in final edited form as: J Phys Chem B. 2011 Oct 28;115(46):13701–13712. doi: 10.1021/jp207265s

Figure 2.

Figure 2

CD spectra recorded for the titration of sequences dG-8 and dG-12 with compound 7 in K+-containing solution. (A) and (C) show changes in the DNA region and (B) and (D) show changes in the ligand (ICD) region during the addition of ligand to dG-8 and dG-12, respectively. Spectral changes with increasing ligand concentration are indicated by blue arrows. The red traces are spectra recorded after addition of 1 and 2 equivalents of ligand, and the dashed traces are spectra of the unmodified DNA. Plots of ICD intensity at 560 nm vs. ligand-to-DNA ratio are shown as insets in (B) and (D).