Skip to main content
. Author manuscript; available in PMC: 2012 Apr 11.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2008 Jan;49(1):320–332. doi: 10.1167/iovs.07-0593

Figure 8.

Figure 8

Simulation of celecoxib drug levels in the retina of BN rats by using the parameter estimates in Table 4 and the model in Figure 5E after administration of 3 mg celecoxib by the periocular route as a solution, suspension, or sustained-release system. The sustained-release system was assumed to have a release rate 1000 times less than the release from suspension. Top: structural model; inset: simulated retinal levels of celecoxib during the initial 12 hours after solution and suspension administration.