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. 2012 Mar 19;6:249. doi: 10.3332/ecancer.2012.249

Figure 1:

Figure 1:

Change of phenotype of a melanoma cell line after cultivation in ES medium. Within ten days, originally adherent, large, elongated cells (A) formed clusters of non-adherent, small, round-shaped cells (B and C). Under ES culture condition, this phenotype remained stable for at least 8 weeks, whereas in standard medium an adherent monolayer was maintained.