Table 1. Treatment-related adverse effects included as attributes in the preference survey and their prevalence at 3-year follow-up in 1381 PCOS participants who had localised prostate cancer at diagnosis and no recurrence at 3 years, and in the subset of 357 men (PCOS cases) who participated in the DCE.

Attribute	Level	Wording	PCOS case participants (n=1381) (%)	DCE case participants (n=357) (%)
Erectile dysfunction	Base	No problems achieving an erection when you want one	27	27
	Mild	Some problems achieving an erection when you want one	33	29
	Severe	Never able to achieve an erection when you want one	40	44
Loss of libido	Base	No change in sexual desire	8	7
	Mild	Less sexual desire	50	43
	Severe	Complete loss of sexual desire	41	51
Urinary leakage	Base	No problems with leaking urine	53	64
	Mild	Occasional problems with leaking urine	33	23
	Severe	Severe problems with leaking urine (no urinary control whatsoever)	14	12
Urinary blockage	Base	No problems with urine blockage	74	67
	Mild	Some problems with urine blockage (have a weak urine stream but get some relief or comfort afterwards)	19	23
	Severe	Severe problems with urine blockage (continually feeling the need to urinate but passing very little with no relief afterwards)	7	10
Bowel symptoms	Base	No bowel problems	79	75
	Mild	Occasional loose bowel movements with discomfort/pain	20	25
	Severe	Very frequent loose bowel movements with discomfort/pain and leakage	1	1
Fatigue	Base	No change in your energy level	47	44
	Mild	Some tiredness and loss of energy	49	51
	Severe	Severe tiredness and loss of energy	4	5
Hormonal effects	Base	No hot flushes or moodiness	88	85
	Mild	Mild hot flushes and moodiness	7	7
	Severe	Severe hot flushes and moodiness	5	8

Abbreviation: PCOS=Prostate Cancer Outcomes Study.