Table 1. Characteristics of the included studies.

Author	Year	Ethnicity	HWE	PCV	AMD	Control	Gene(s)/locus investigated	Ref.
Gotoh	2004	Japanese	yes	58	85	82	APOE	[15]
Gotoh	2008	Japanese	no	204	116	-	HTRA1, CFH	[35]
Gotoh	2009	Japanese	yes	55	56	77	LOC387715	[24]
Gotoh	2010	Japanese	yes	181	84	276	LOC387715, HTRA1	[25]
Yamashiro	2011	Japanese	no	518	408	336	Elastin	[20]
Yamashiro	2011	Japanese	no	154	216	142	Elastin	[20]
Nakanishi	2010	Japanese	yes	375	-	847	LOC387715, CFH	[26]
Hayashi	2010	Japanese	yes	518	408	1351	LOC387715, CFH	[27]
Nakata	2011	Japanese	yes	167	-	-	PEDF, SERPINF1	[49]
Nakata	2011	Japanese	yes	510	401	336	SERPING1	[37]
Tsujikawa	2011	Japanese	no	88	-	-	LOC387715	[45]
Kondo	2007	Japanese	yes	76	73	94	LOC387715, HTRA1	[16]
Kondo	2008	Japanese	yes	103	78	104	Elastin	[17]
Kondo	2009	Japanese	yes	130	-	173	CFH	[21]
Kondo	2009	Japanese	yes	136	-	183	CFB, C2, RDBP, SKIV2L	[21]
Kondo	2009	Japanese	yes	140	116	189	SOD2	[40]
Bessho	2009	Japanese	yes	140	116	189	PEDF	[38]
Bessho	2011	Japanese	no	119	68	-	LOC387715	[34]
Sakurada	2008	Japanese	yes	109	-	85	LOC387715	[30]
Sakurada	2009	Japanese	yes	92	-	-	LOC387715	[44]
Sakurada	2010	Japanese	yes	71	-	-	LOC387715	[18]
Sakurada	2011	Japanese	yes	226	-	-	LOC387715, CFH	[23]
Goto	2009	Japanese	yes	100	100	190	LOC387715, CFH, C3	[29]
Fuse	2011	Japanese	yes	60	50	138	LOC387715, LOXL1	[28]
Tanaka	2011	Japanese	yes	287	-	277	LOC387715, CFH	[31]
Park	2011	Korea	yes	103	-	112	LOC387715, HTRA1	[33]
Park	2011	Korea	yes	51	-		LOC387715, HTRA1	[43]
Li	2010	Chinese	yes	118	-	115	SERPING1	[36]
Zhang	2011	Chinese	yes	177	131	182	9p21	[42]
Wu	2011	Chinese	yes	177	131	182	PEDF	[39]
Sng	2011	Chinese	yes	120	126	274	Toll-like receptor 3	[41]
Lee	2008	Chinese	yes	72	-	93	LOC387715, CFH, CFB, C2	[32]
Lima	2011	Caucasian	no	56	368	368	Elastin	[19]
Lima	2010	Caucasian	no	55	368	368	LOC387715, CFH, CFB, C2	[22]

HWE: Hardy–Weinberg equilibrium; PCV: polypoidal choroidal vasculopathy; AMD: Age-related macular degeneration. Ref: Reference