Table 1. Top SNPs associated with sexual function related measures in a cohort of females of European ancestry.
Phenotype | SNP | CHR | Position | Locus | Allele | Effect * | s.e.m | P |
Arousal | rs13202860 | 6 | 87211973 | A | −0.421 | 0.08 | 1.213E−07 | |
Arousal | rs1876525 | 6 | 87208811 | C | −0.421 | 0.08 | 1.213E−07 | |
Arousal | rs13209281 | 6 | 87201368 | A | −0.443 | 0.09 | 8.329E−07 | |
Overall FSD | rs4820255 | 22 | 35533796 | PVALB | C | −0.366 | 0.076 | 1.687E−06 |
Overall FSD | rs4821535 | 22 | 35533452 | PVALB | G | −0.366 | 0.076 | 1.687E−06 |
Overall FSD | rs2284024 | 22 | 35528729 | PVALB | T | −0.366 | 0.077 | 1.838E−06 |
Overall FSD | rs5750311 | 22 | 35533286 | PVALB | G | −0.367 | 0.077 | 2.104E−06 |
Overall FSD | rs739031 | 22 | 35532649 | PVALB | T | −0.364 | 0.077 | 2.144E−06 |
Overall FSD | rs4821536 | 22 | 35533947 | PVALB | T | −0.355 | 0.076 | 3.196E−06 |
Lubrication | rs2370759 | 22 | 32674978 | EPC1 | G | 0.237 | 0.05 | 1.7E−06 |
Lubrication | rs11594963 | 10 | 32665742 | EPC1 | G | 0.236 | 0.05 | 1.95E−06 |
Lubrication | rs11599044 | 10 | 32655451 | EPC1 | A | 0.236 | 0.05 | 1.95E−06 |
Lubrication | rs10508773 | 10 | 32615450 | EPC1 | C | 0.234 | 0.05 | 1.952E−06 |
Lubrication | rs16933243 | 10 | 32655141 | EPC1 | T | 0.233 | 0.05 | 2.565E−06 |
Lubrication | rs11008865 | 10 | 32614848 | EPC1 | C | 0.232 | 0.05 | 2.704E−06 |
Effect, β coefficient of linear regression. The effect sizes denote changes in phenotype unit per each additional copy of the reference allele.