Table 2. SNP genotypes of the family within the two genes SLC11A2 and TMPRSS6.
SLC11A2 | TMPRSS6 | ||||||
rs6580779 | rs161044 | rs150909 | rs149411 | rs11704654 | rs4820268 | rs855791 | |
Chromosome:Base pair position | 12:51420164 | 12:51382232 | 12:51381077 | 12:51380232 | 22:37499386 | 22:37469591 | 22:37462936 |
Located in: | 5′UTR | Intron | 3′UTR | 3′UTR | Exon 2 | Exon 13 | Exon 17 |
Ancestral/derived allele: | A/C | C/T | T/C | A/G | C/T | A/G | G/A |
SNP effect: | - | - | - | - | Syn. | Syn. | V736A |
Father | 1 | 1 | 1 | 1 | 0 | 1 | 2 |
Mother | 1 | 1 | 1 | 1 | 2 | 1 | 1 |
Son 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Son 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 |
Daughter 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 |
Daughter 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Coding of genotypes | |||||||
0 = | AA | CC | TT | GG | CC | AA | GG |
1 = | AC | CT | TC | GA | CT | AG | GA |
2 = | CC | TT | CC | AA | TT | GG | AA |