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. 2012 Apr 11;7(4):e35115. doi: 10.1371/journal.pone.0035115

Figure 7. SLPI expression by human astrocytes and microglia.

Figure 7

Astrocyte or microglial cultures were treated with IFNγ ± IL-1, LPS, poly IC, IL-4 or IL-13 and SLPI expression was examined by ELISA (24 h) or Q-PCR (6 h stimulation). (A) Representative ELISA data from astrocytes and microglia are shown. Results show that SLPI is produced by activated astrocytes. Results are mean ± SD and are representative of 3–5 separate cases. (B) Pooled normalized Q-PCR data (n = 3) show that SLPI mRNA was induced by proinflammatory stimuli (astrocytes>>microglia). * p<0.05, ** p<0.01, *** p<0.001.