Table 4. The expression of nkTPathway (natural killer T-cell) genes in atherosclerotic plaques from carotid arteries, aortas and femoral arteries compared to non-atherosclerotic internal thoracic arteries analyzed with TaqMan low density array.
| Gene abbreviation | Gene ID | Average FC |
| CSF2 (colony stimulating factor 2 (granulocyte-macrophage) | 1437 | ↑↑↑* |
| IL12B (interleukin 12B) | 3593 | ↑↑* |
| CCR5 (chemokine (C-C motif) receptor 5) | 1234 | 14.9 (p<0.001) |
| CXCR4 (chemokine (C-X-C motif) receptor 4) | 7852 | 12.4 (p=0.001) |
| CCR1 (chemokine (C-C motif) receptor 1) | 1230 | 10.7 (p<0.001) |
| CD4 (CD4 molecule) | 920 | 10.2 (p<0.001) |
| CCL4 (chemokine (C-C motif) ligand 4) | 6351 | 8.4 (p=0.001) |
| CCR7 (chemokine (C-C motif) receptor 7) | 1236 | 8.1 (p=0.001) |
| CCL3 (chemokine (C-C motif) ligand 3) | 6348 | 6.6 (p<0.001) |
| IL12RB1 (interleukin 12 receptor, beta 1) | 3594 | 6.0 (p<0.001) |
| CD28 (CD28 molecule) | 940 | 5.8 (p=0.001) |
| CXCR3 (chemokine (C-X-C motif) receptor 3) | 2833 | 5.6 (p=0.001) |
| CCR4 (chemokine (C-C motif) receptor 4) | 1233 | 3.5 (p=0.033) |
| CD40LG (CD40 ligand) | 959 | 3.4 (p=0.008) |
| IFNG (interferon, gamma) | 3458 | 3.1 (p=0.022) |
| IL12RB2 (interleukin 12 receptor, beta 2) | 3595 | 3.0 (p=0.233) |
| IFNGR2 (interferon gamma receptor 2) | 3460 | 2.9 (p<0.001) |
| IL12A (interleukin 12A) | 3592 | 2.9 (p=0.009) |
| TGFB1 (transforming growth factor, beta 1) | 7040 | 2.0 (p<0.001) |
| IL18R1 (interleukin 18 receptor 1) | 8809 | 2.0 (p=0.007) |
| CCR2 (chemokine (C-C motif) receptor 2) | 1231 | 1.9 (p=0.213) |
| IFNGR1 (interferon gamma receptor 1) | 3459 | 1.7 (p=0.005) |
| IL4R (interleukin 4 receptor) | 3566 | 1.4 (p=0.002) |
| TGFB2 (transforming growth factor, beta 2) | 7042 | 1.4 (p=0.069) |
| IL5 (interleukin 5) | 3567 | 1.5 (p=0.500) |
| IL4 (interleukin 4) | 3565 | −1.2 (p=0.468) |
| IL2 (interleukin 2) | 3558 | −2.1(p=0.836) |
| TGFB3 (transforming growth factor, beta 3) | 7043 | 1.2 (p=0.350) |
| CCR3 (chemokine (C-C motif) receptor 3) | 1232 | −1.7 (p=0.108) |
Fold changes (FC) are calculated by comparing the median expression of genes in atherosclerotic arteries vs. controls. Notes.
*
Highly expressed in atherosclerotic plaque.