Table 3. Meta-analysis of the rs961253 in association with colorectal cancer risk under different genetic models.

Variables	Case/control	Genetic model	OR (95%CI)	P	I2 (%)	P for heterogeneity
Total (N = 17)	29859/29696	CA versus CC	1.14 (1.10–1.18)	<0.001	24.9	0.167
		AA versus CC	1.25 (1.16–1.34)	<0.001	31.8	0.102
		Dominant model	1.17 (1.12–1.22)	<0.001	32.1	0.099
		Additive model	1.13 (1.09–1.18)	<0.001	46.2	0.019
Ethnicity
European (N = 14)	26220/25650	CA versus CC	1.12 (1.08–1.16)	<0.001	0.0	0.691
		AA versus CC	1.23 (1.17–1.30)	<0.001	0.0	0.539
		Dominant model	1.14 (1.10–1.18)	<0.001	0.0	0.555
		Additive model	1.11 (1.08–1.14)	<0.001	0.0	0.471
Asian (N = 3)	3639/4046	CA versus CC	1.37 (1.21–1.54)	<0.001	0.0	0.463
		AA versus CC	1.63 (0.44–6.05)	0.465	77.2	0.012
		Dominant model	1.39 (1.21–1.60)	<0.001	22.4	0.276
		Additive model	1.34 (1.20–1.50)	0.001	53.5	0.116