Table 1. Probes depleted in bicalutamide-treated LNCaP cells.
shRNA target gene | Description | Probes scored* | log2 (Bic/Veh)** | p value |
STRN3 | Striatin, calmodulin binding protein 3, cell cycle protein | 2 | −1.527 −1.008 | 0.0037 0.0073 |
STRADA | STE20-related kinase adaptor alpha | 1 | −1.197 | 0.0003 |
TTK | Ser/Thr/Tyr kinase, cell cycle regulated | 3 | −1.014 −1.018 −0.991 | 0.0039 0.0040 0.0073 |
MAST3 | Microtubule associated Ser/Thr kinase 3 | 1 | −0.901 | 0.0009 |
PSMC1 | Proteasome 26S subunit ATPase 1 | 2 | −0.900 −0.880 | 0.0048 0.0060 |
CIT | Citron, Rho-interacting, Ser/Thr kinase 21 | 2 | −0.802 −0.815 | 9.12E-05 0.0001 |
RABGAP1 | GTPase-activating protein of RAB6A, microtubule/centrosome function | 1 | −0.791 | 0.0035 |
PRKACG | Gamma form of Protein Kinase A catalytic subunit | 1 | −0.758 | 0.0043 |
IGF1R | Insulin-like growth factor 1 receptor | 2 | −0.716 −0.681 | 0.0047 0.0091 |
TSSK2 | Testes-specific serine kinase 2 | 1 | −0.666 | 0.0045 |
VEGFβ | Vascular endothelial growth factor beta | 2 | −0.660 −0.594 | 0.0015 0.0026 |
MAPKAPK5 | Mitogen-activated protein kinase-activated protein kinase 5 | 1 | −0.645 | 0.0095 |
ABL2 | V-abl Abelson murine leukemia viral oncogene homolog 2, tyrosine kinase | 1 | −0.621 | 0.0047 |
PLK2 | Polo-like kinase 2, Ser/Thr kinase | 2 | −0.598 −0.584 | 0.0045 0.0085 |
AKT1 | Ser/Thr kinase | 1 | −0.594 | 0.0041 |
Number of probes that had a log2 value ≤−0.58.
Bic, bicalutamide; Veh, vehicle.