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. 2012 Apr 11;7(4):e34344. doi: 10.1371/journal.pone.0034344

Table 1. Subject Characteristics.

Characteristic Bivalirudin Heparin P value
(n = 8) (n = 8)
Clinical Characteristics
Age (years) 59.8±12.2 62.8±11.2 0.6
Sex (% men) 87.5 87.5 0.5
Race (% Caucasian) 87.5 100 0.2
Height (cm) 174.7±10 173.8±12.4 0.9
Weight (kg) 90±13.4 101.7±21.8 0.2
BSA (m2) 2.1±0.2 2.1±0.3 0.4
BMI 29.5±4.5 3.9±7.8 0.3
Past Medical History (%)
Hypertension 87.5 87.5 0.5
Diabetes mellitus 12.5 50 0.1
Active tobacco use 25 0 0.1
Coronary artery disease 25 62.5 0.04
Hypercholesterolemia 87.5 87.5 0.5
Myocardial infarction 12.5 12.5 0.5
Cerebrovascular disease 0 0 N/A
Peripheral vascular disease 25 0 0.1
Atrial fibrillation 0 12.5 0.2
Medications (%)
Aspirin 87.5 87.5 0.5
Clopidogrel 87.5 87.5 0.5
β-blocker 87.5 75 0.3
Angiotensin converting enzyme inhibitor 12.5 62.5 0.02
Calcium channel blocker 12.5 12.5 0.5
Angiotensin-receptor-blocker 25 0 0.1
Aldosterone antagonist 0 0 N/A
Diuretic 0 0 N/A
Anti-lipid agent 87.5 87.5 0.5
Lab Values
Na+ 139.6±2.9 137.9±0.8 0.07
K+ 4.2±0.4 4.1±0.3 0.6
Cl- 106.1±3.5 103.8±0.9 0.06
CO2 26±1.7 26.9±1.2 0.3
BUN 14.5±3.0 14.6±6.6 0.9
Creatinine 1.0±0.4 0.9±0.3 0.9
Glucose 111.6±22.5 120.9±24.1 0.3
White blood cells 7.4±1.7 8.1±2.0 0.6
Hemoglobin 14.1±1.2 12.5±1.3 0.05
Platelets 185.8±22.8 188.6±44.9 0.9
Prothrombin time 12.4±0.7 12.8±0.7 0.5
PTT 22.5±2.8 30.5±13.2 0.2
INR 1.0±0.1 1.1±0.1 0.4
EF (%) 60.2±9.9 52.5±8.8 0.4