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. 2012 Apr 11;7(4):e34959. doi: 10.1371/journal.pone.0034959

Figure 3. Enhanced colon tumor development in IL-17F-deficient mice.

Figure 3

(A) Immunohistochemistry stainings of colon sections from WT mice using anti-IL-17F and IL-17A antibodies. Bar = 10 µm. (B) Tumor images, (C) Tumor numbers and (D) Tumor areas from the colons of AOM-DSS treated WT, Il-17a−/− and Il-17f−/− mice. Data shown are a combination of 2 independent experiments (WT, n = 8, Il-17a−/−, n = 6, and Il-17f−/−, n = 8). *, P<0.05. **, P<0.005. (E) H&E stainings of the tumor sections. Arrows pointed out vascular tubes in the basal layer (At least 3 mice from each group were analyzed and representative picture were shown). Bar = 100 µm.