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Summary of studies of the transforming efficiency of mutant p185neu forms coexpressed with the EGFR
| Cell lines | 0.3% agar
|
0.33% agar
|
||
|---|---|---|---|---|
| EGF (+) | (−) | (+) | (−) | |
| NE99 | 67 | 7 | 31 | 9.5 |
| NE/Tex | 25.5 | 2.5 | 1.5 | 1.5 |
| NE/Tex4 | 29.5 | 5.5 | 0 | 2 |
| NE/Tex6CN | 7.5 | 1 | 0.5 | 0 |
| NR6 | 1 | 1 | 1.5 | 1.5 |
Anchorage-independent growth was determined as described in Materials and Methods. The number of average colonies obtained by each clone is indicated.
