Table 3.
Serum and colon levels of total tocopherols and their metabolites
Group | α-T | γ-T | δ-T | γ-CEHC | δ-CEHC | γ-CMBHC | δ-CMBHC | γ-CDMDHC | δ-CDMDHC |
---|---|---|---|---|---|---|---|---|---|
Serum Levels (μM) | |||||||||
Control | 14.39 ± 6.13 | 0.09 ± 0.02 | 0.02 ± 0.01 | 0.01 ± 0.00 | 0.13 ± 0.02 | 0.02 ± 0.00 | 0 | 0 | 0 |
0.2% α-T | 30.65 ± 6.28‡ | 0.16 ± 0.06 | 0.09 ± 0.03 | 0.04 ± 0.01 | 0.32 ± 0.03 | 0 | 0 | 0 | 0 |
0.2% γ-T | 4.51 ± 4.35† | 21.20 ± 9.56‡ | 0.02 ± 0.00 | 6.07 ± 1.77‡ | 0.14 ± 0.00 | 0.12 ± 0.04‡ | 0 | 0.10 ± 0.04‡ | 0 |
0.2% δ-T | 7.74 ± 4.58 | 1.17 ± 0.71 | 6.69 ± 3.63‡ | 0.49 ± 0.21 | 23.32 ± 5.29‡ | 0.02 ± 0.00 | 0.23 ± 0.08‡ | 0 | 0.70±0.01‡ |
Colon Levels (nmol/g) | |||||||||
Control | 18.85 ± 2.80 | 0.38 ± 0.39 | 0.02 ± 0.01 | 0.05 ± 0.04 | 0.12 ± 0.10 | 0 | 0 | 0 | 0.15 ± 0.07 |
0.2% α-T | 34.83 ± 1.92‡ | 0.47 ± 0.32 | 0.04 ± 0.02 | 0.15 ± 0.20 | 1.29 ± 1.42 | 0.13 ± 0.20 | 0 | 0 | 0.21 ± 0.04 |
0.2% γ-T | 13.44 ± 1.52† | 21.49 ± 3.26‡ | 0.05 ± 0.06 | 6.91 ± 7.62† | 0.16 ± 0.07 | 0.65 ± 1.01 | 0 | 0.05 ± 0.03‡ | 0.17 ± 0.05 |
0.2% δ-T | 18.05 ± 0.88 | 1.52 ± 0.71 | 16.91 ± 7.11‡ | 0.37 ± 0.34 | 7.60 ± 4.95‡ | 0.04 ± 0.04 | 0.36 ± 0.27‡ | 0.05 ± 0.02‡ | 0.37 ± 0.06‡ |
Note: The samples were from the short term experiment. Values are mean ± SD. n = 5.
The value is different from that of the AOM-treated positive control group (p < 0.05 by the ANOVA-Dunnett’s test).
p < 0.01 by the ANOVA-Dunnett’s test.