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. Author manuscript; available in PMC: 2013 Apr 15.
Published in final edited form as: J Immunol. 2012 Mar 16;188(8):3993–4000. doi: 10.4049/jimmunol.1103301

Figure 1. The mtdEY04695 mutant phenocopies IMD pathway mutants.

Figure 1

(A) Fractional survival during oral V. cholerae infection of the control strain yw (WT), the transposon insertion line mtdEY04695, and the IMD pathway mutants, dreddB118 and key1. Log-rank analysis demonstrated a statistically significant difference between survival of control flies and mtdEY04695 mutants (p < 0.001), key1 mutants (p < 0.001), and dreddB118 mutants (p < 0.05). (B) Bacterial burden of yw, mtdEY04695, dreddB118 and key1 flies after 48 hours of infection. There was a statistically significant difference in bacterial burden between control flies and mtdEY04695 (p=0.0022) or key1 (p=0.0022) mutant flies. However, the difference in bacterial burden between control flies and dreddB118 mutant flies was not statistically significant (p=0.0931).