Table 1.
Socio-demographic data, clinical measures, and laboratory markers of HIV-2-infected and HIV-negative participants in a community cohort in Guinea-Bissau in 2003
| Characteristics | HIV-2, n (%)a (n = 146) |
HIV-negative, n (%)a (n = 197) |
p-Value |
|---|---|---|---|
| Gender | |||
| Male | 47 (32) | 54 (27) | 0.3 |
| Female | 99 (68) | 143 (73) | |
| Age (years) | |||
| 15–29 | 4 (3) | 23 (12) | 0.01 |
| 30–44 | 35 (24) | 50 (25) | |
| 45–59 | 47 (32) | 47 (24) | |
| 60+ | 60 (41) | 77 (39) | |
| Mean (SD) | 55.9 (15) | 52.8 (18) | 0.1 |
| Ethnic group | |||
| Manjako | 146 (100) | 189 (96) | 0.01 |
| Other | 0 | 8 (4) | |
| Zone | |||
| Central | 115 (79) | 154 (78) | 0.9 |
| Peripheral | 31 (21) | 43 (22) | |
| Marital status | |||
| Single | 22 (15) | 35 (18) | 0.3 |
| Married | 104 (71) | 145 (74) | |
| Divorced/widowed | 20 (14) | 17 (9) | |
| BMI (kg/m2)b | |||
| <18.5 | 24 (17) | 21 (11) | 0.1 |
| ≥18.5 | 121 (83) | 176 (89) | |
| Median (IQR) | 21.6 (19.7–24.4) | 21.8 (19.6–24.3) | 0.6 |
| MUAC (mm)c | |||
| <230 W or <240 M | 12 (8) | 10 (5) | 0.2 |
| ≥230 W or ≥240 M | 134 (92) | 187 (95) | |
| Mean (SD) | 278.7 (36.5) | 282.3 (37.2) | 0.4 |
| WHO clinical staged | |||
| 1 | 105 (72) | 163 (83) | 0.05 |
| 2 | 20 (14) | 15 (8) | |
| 3/4 | 21 (14) | 19 (10) | |
| WHO performancee,f | |||
| 1 | 57 (40) | 92 (47) | 0.4 |
| 2 | 57 (40) | 69 (35) | |
| 3/4 | 30 (21) | 34 (17) | |
| CD4%g | |||
| <14 | 6 (4) | 0 | <0.001 |
| 14-28 | 41 (30) | 5 (3) | |
| >28 | 92 (66) | 183 (97) | |
| Median (IQR) | 31 (26–38) | 40 (36–46) | <0.001 |
| PVL (copies/ml) | |||
| <100 | 42 (29) | ||
| 100–9999 | 74 (51) | ||
| 10 000–99 999 | 23 (16) | ||
| ≥100 000 | 7 (5) | ||
| Median (IQR) | 1124 (50–6792) | ||
BMI, body mass index; MUAC, mid-upper arm circumference; WHO, World Health Organization; PVL, plasma viral load; SD, standard deviation; IQR, interquartile range.
a
Unless otherwise indicated.
b
One missing value.
c
Cut-offs: 230 mm for women (W) and 240 mm for men (M).
d
WHO clinical stage assigned using an algorithm based on WHO staging criteria for HIV infection (2006 revision25).
e
Four missing values.
f
WHO performance scale: 1 (asymptomatic, normal activity), 2 (symptomatic, normal activity), 3 (bedridden <50% of the day), 4 (symptomatic and bedridden >50% of the day).
g
Sixteen missing values.