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Isolated rat Sertoli cells (SCs) preloaded with FITC-labeled nanoparticles imaged by DIC (a, c) and fluorescence microscopy (b, d). SCs in (a, b) were incubated with the nanoparticles (green) and SCs in (c, d) were not. Inset: This culture of isolated SCs shows contaminating peritubular cells (arrows) that do not phagocytose the nanoparticles, indicating selective phagocytosis by SCs. Magnifications are the same in (a–d).
