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. 2012 Apr 12;2:362. doi: 10.1038/srep00362

Figure 6. Effects of metformin on the radiosensitivity of CSCs or CS-like cells.

Figure 6

(A) MCF-7 cells were irradiated, incubated with or without 1 mM metformin for 48 h and analyzed for CD44high/CD24low cells. (B) % of CD44high/CD24low MCF-7 cells after irradiation and 48 h incubation with 1 mM metformin. Means of 5 experiments ± 1 S.E. *P < 0.05 for IR-induced increases. **P < 0.05 between IR and IR + Metformin. (C) % of ALDH1-positive FSaII cells after irradiation and 48 h incubation with 1 mM metformin. Means of 5 experiment ± 1 S.E. *P < 0.05 for IR-induced increases. **P < 0.05 between IR and IR + 1 mM Metformin groups.