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VEGFR pathways within the tumor cell.
Abbreviations: AKT, serine/threonine protein kinase; FAK, focal adhesion kinase-1; MAPK, mitogen-activated protein kinase; NOS, nitric oxide synthase; PI3K, phosphoinositide 3-kinase; PLC, phospholipase; PKC, protein kinase; Shc, proteins containing Src homology-2 domains; RAS, rat sarcoma; VEGF, vascular endothelial growth factor; VEGFR, VEGF receptor.
