FIG. 5.

Systemic immune consequences in IgG versus anti-CD1d treated mice. Uninjured mice were dosed with either IgG or anti-CD1d mAb; 24 h later, the animals were euthanized and splenocytes cell suspensions stained and analyzed by flow cytometry. Results are displayed as the percentage of live cells positive for the cell surface markers indicated (A). In separate experiments, uninjured mice were dosed with either IgG or anti-CD1d mAb; 24 h later, the animals were euthanized and whole blood collected via cardiac puncture. Serum was analyzed for the chemokines indicated by ELISA (B); n = 4 per group.