Table 1.
IC50 values for FdUMP[10], 5-FU, Dox, and Ara-C
| Chemotherapy | HL60 | Jurkat | THP-1 | K562 | KG1a | Molm-13 |
|---|---|---|---|---|---|---|
| FdUMP[10], nM | 3.4 (2.984-3.825) | 5.4 (4.609-6.417) | 4.1 (3.413-4.907) | 21.5 (14.85-30.99) | 4.9 (3.995-6.043) | 10.01 (8.726-11.49) |
| 5-FU, nM | 5027 (3804-6643) | 7,492 (6,169-9,100) | 1157 (943-1421) | 7011 (3270-15 030) | 5277 (3902-7139) | 943.4 (895-994) |
| Dox, nM | 21.7 (18.90-24.97) | 75.2 (48.16-117.47) | 160.5 (75.7-340.5) | 252.9 (200.69-319.14) | 1337 (1190-1510) | 8.18 (6.41-10.43) |
| Ara-C, nM | 144.9 (85.00-247.0) | 15.5 (14.44-16.67) | 6,700 (5890-7534) | 83.7 (72.24-96.94) | 195.8 (163.5-234.4) | 41.24 (12.95-131.3) |
Values are mean (95% CI).