Mean ± SEM activity counts in 18-month old offspring (averaged across sex) following pretreatment with amphetamine. Although there were significant effects of amphetamine dose and time, prenatal arsenic exposure did not interact with amphetamine treatment. Within each amphetamine dose group, data were averaged across prenatal arsenic conditions for this figure. Sample size: 0 ppm n = 5 litters, 8 ppm n = 5, 25 ppm n = 5, 80 ppm n = 5.