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. 2012 Mar 21;32(12):4196–4211. doi: 10.1523/JNEUROSCI.3094-11.2012

Table 1.

Measurements of synaptic vesicle accumulation

Ventral cord
Dorsal cord
Area ± SEM (n)a Maximum (μm2) Density ± SEM (n)b Area ± SEM (n)a Maximum (μm2) Density ± SEM (n)b
GABAergic
    Wild type 0.80 ± 0.02 (530) 3.9 25.7 ± 1.0 (16) 0.83 ± 0.03 (344) 3.0 22.9 ± 0.9 (10)
    fmi-1(ju43) 1.10 ± 0.13 (102)* 8.0 21.7 ± 0.9 (4)* 1.27 ± 0.08 (157)* 4.8 23.4 ± 0.7 (4)
    fmi-1(ju58) 1.80 ± 0.14 (328)* 17.4 17.6 ± 2.4 (9)* 1.15 ± 0.06 (233)* 7.0 21.7 ± 3.9 (6)
    fmi-1(tm306) 1.43 ± 0.15 (199)* 19.7 19.2 ± 1.9 (5)* 0.89 ± 0.05 (147) 3.4 18.4 ± 3.0 (4)*
    fmi-1(rh308) 1.74 ± 0.20 (118)* 18.9 16.3 ± 1.2 (4)* 0.91 ± 0.05 (147) 3.8 19.0 ± 1.5 (3)
    fmi-1(ju58)+[WRM066DB07] 1.15 ± 0.10 (167)* 9.0 19.9 ± 1.7 (7)* 1.24 ± 0.10 (119)* 7.7 17.5 ± 1.8 (4)*
    juIs1+[WRM0066DB07) 0.86 ± 0.06 (203) 6.0 26.5 ± 2.0 (6) 0.92 ± 0.06 (184) 6.0 23.1 ± 1.5 (5)
    fmi-1(tm306)+[Pacr-2::fmi-1] 1.06 ± 0.07 (129)* 4.6 15.5 ± 2.4 (4)* 1.22 ± 0.09 (110)* 3.8 17.2 ± 2.2 (4)
    fmi-1(tm306)+[Punc-25::fmi-1] 2.11 ± 0.22 (135)* 16.8 12.3 ± 2.4 (5)* 1.14 ± 0.11 (77)* 4.4 20.0 ± 4.4 (4)
    cdh-4(lq83) 1.82 ± 0.11 (259)* 14.7 16.6 ± 1.6 (7)* 1.24 ± 0.09 (169)* 7.2 20.3 ± 2.0 (4)*
    fmi-1(tm306);cdh-4(lq83) 1.45 ± 0.13 (171)* 13.2 16.6 ± 1.8 (5)* 0.97 ± 0.07 (134)* 6.0 18.1 ± 2.6 (4)*
    cdh-4(lq56) 1.40 ± 0.10 (155)* 6.7 16.7 ± 3.6 (5)* N/D
    fmi-1(tm306);cdh-4(lq56) 1.48 ± 0.18 (113)* 12.8 18.1 ± 1.0 (3)* N/D
    eri-1(mg366)juIs1;CDH-4(RNAi) 1.56 ± 0.15 (137)* 11.3 16.7 ± 1.8 (4)* N/D
    fmi-1(tm306); eri-1(mg366)juIs1;CDH-4(RNAi) 1.57 ± 0.24 (101)* 18.9 17.8 ± 3.1 (4)* N/D
Cholinergic
    Wild type 0.90 ± 0.06 (281) 6.2 26.7 ± 2.0 (5) 1.03 ± 0.07 (208) 6.0 26.1 ± 2.8 (4)
    fmi-1(ju58) 0.98 ± 0.06 (459) 10.9 23.8 ± 2.1 (9) 1.17 ± 0.09 (323)* 16.6 26.9 ± 2.5 (7)

N/D, Not determined.

aMeasurements are in square micrometers.

bAverage number of puncta observed per 100 μm.

*p < 0.01, significantly different from wild type;

p < 0.01, significantly different than fmi-1;

not significantly different from fmi-1(tm306).