Table 1.
Ventral cord |
Dorsal cord |
|||||
---|---|---|---|---|---|---|
Area ± SEM (n)a | Maximum (μm2) | Density ± SEM (n)b | Area ± SEM (n)a | Maximum (μm2) | Density ± SEM (n)b | |
GABAergic | ||||||
Wild type | 0.80 ± 0.02 (530) | 3.9 | 25.7 ± 1.0 (16) | 0.83 ± 0.03 (344) | 3.0 | 22.9 ± 0.9 (10) |
fmi-1(ju43) | 1.10 ± 0.13 (102)* | 8.0 | 21.7 ± 0.9 (4)* | 1.27 ± 0.08 (157)* | 4.8 | 23.4 ± 0.7 (4) |
fmi-1(ju58) | 1.80 ± 0.14 (328)* | 17.4 | 17.6 ± 2.4 (9)* | 1.15 ± 0.06 (233)* | 7.0 | 21.7 ± 3.9 (6) |
fmi-1(tm306) | 1.43 ± 0.15 (199)* | 19.7 | 19.2 ± 1.9 (5)* | 0.89 ± 0.05 (147) | 3.4 | 18.4 ± 3.0 (4)* |
fmi-1(rh308) | 1.74 ± 0.20 (118)* | 18.9 | 16.3 ± 1.2 (4)* | 0.91 ± 0.05 (147) | 3.8 | 19.0 ± 1.5 (3) |
fmi-1(ju58)+[WRM066DB07] | 1.15 ± 0.10 (167)*‡ | 9.0 | 19.9 ± 1.7 (7)*‡ | 1.24 ± 0.10 (119)* | 7.7 | 17.5 ± 1.8 (4)* |
juIs1+[WRM0066DB07) | 0.86 ± 0.06 (203) | 6.0 | 26.5 ± 2.0 (6) | 0.92 ± 0.06 (184) | 6.0 | 23.1 ± 1.5 (5) |
fmi-1(tm306)+[Pacr-2::fmi-1] | 1.06 ± 0.07 (129)*‡ | 4.6 | 15.5 ± 2.4 (4)*‡ | 1.22 ± 0.09 (110)* | 3.8 | 17.2 ± 2.2 (4) |
fmi-1(tm306)+[Punc-25::fmi-1] | 2.11 ± 0.22 (135)* | 16.8 | 12.3 ± 2.4 (5)* | 1.14 ± 0.11 (77)* | 4.4 | 20.0 ± 4.4 (4) |
cdh-4(lq83) | 1.82 ± 0.11 (259)* | 14.7 | 16.6 ± 1.6 (7)* | 1.24 ± 0.09 (169)* | 7.2 | 20.3 ± 2.0 (4)* |
fmi-1(tm306);cdh-4(lq83) | 1.45 ± 0.13 (171)*† | 13.2 | 16.6 ± 1.8 (5)*† | 0.97 ± 0.07 (134)* | 6.0 | 18.1 ± 2.6 (4)* |
cdh-4(lq56) | 1.40 ± 0.10 (155)* | 6.7 | 16.7 ± 3.6 (5)* | N/D | ||
fmi-1(tm306);cdh-4(lq56) | 1.48 ± 0.18 (113)*† | 12.8 | 18.1 ± 1.0 (3)*† | N/D | ||
eri-1(mg366)juIs1;CDH-4(RNAi) | 1.56 ± 0.15 (137)* | 11.3 | 16.7 ± 1.8 (4)* | N/D | ||
fmi-1(tm306); eri-1(mg366)juIs1;CDH-4(RNAi) | 1.57 ± 0.24 (101)*† | 18.9 | 17.8 ± 3.1 (4)*† | N/D | ||
Cholinergic | ||||||
Wild type | 0.90 ± 0.06 (281) | 6.2 | 26.7 ± 2.0 (5) | 1.03 ± 0.07 (208) | 6.0 | 26.1 ± 2.8 (4) |
fmi-1(ju58) | 0.98 ± 0.06 (459) | 10.9 | 23.8 ± 2.1 (9) | 1.17 ± 0.09 (323)* | 16.6 | 26.9 ± 2.5 (7) |
N/D, Not determined.
aMeasurements are in square micrometers.
bAverage number of puncta observed per 100 μm.
*p < 0.01, significantly different from wild type;
‡p < 0.01, significantly different than fmi-1;
†not significantly different from fmi-1(tm306).