Table 2. Evidence of positive Darwinian selection from site-specific model analyses for the HAMP gene of mammalians.
1 | −989.958 | K = 2.090,ω = 0.357 | None | ||
M3 (discrete) | 5 | −962.409 | M3 vs M0, 2ΔLnL = 55.10, df = 4, p = 0.00 | K = 2.375, p 0 = 0.467, p 1 = 0.185, p 2 = 0.348,ω 0 = 0.043ω 1 = 0.459,ω 2 = 1.303 | Not analyzed |
M1a (Nearly Neutral) | 1 | −962.584 | K = 2.317, p 0 = 0.526, p 1 = 0.474,ω 0 = 0.056,ω 1 = 1.0 | Not allowed | |
M2a (Positive Selection) | 3 | −962.462 | M2 vs M1, 2ΔLnL = 0.24, df = 2, p = 0.88 | K = 2.374, p 0 = 0.531, p 1 = 0.381, p 2 = 0.087,ω 0 = 0.061,ω 1 = 1,ω 2 = 1.664 | M0 (One ration) |
M7 (beta) | 2 | −963.172 | K = 2.284, P = 0.180, q = 0.206 | Not allowed | |
M8 (beta and omega) | 4 | −962.411 | M8 vs M7, 2ΔLnL = 1.52, df = 2, p = 0.47 | K = 2.369, P 0 = 0.623, p 1 = 0.377, p = 0.469, q = 2.968,ω = 1.258 |
Note: P number of parameters in the ω distribution, K estimated transition/transversion rate ration, ω selection parameter, and p n proportion of sites that fall into the ωn site class. p, q shape parameters of the β function (for models M7 and M8).