Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
This figure presents cell survival and growth signaling pathways within a CML cell. Red squares represent proteins encoded by genes targeted by the deregulated miRNAs. We have shown that the miRNAs regulating these target genes are downregulated in CML. As a result, these target genes are probably upregulated leading to increased cell survival and induced of uncontrolled cell proliferation.
