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. 2012 Apr 12;7(4):e34372. doi: 10.1371/journal.pone.0034372

Figure 8. Proportion of Patients with Loss of Resistant Variants after Treatment Failure during Follow-up.

Figure 8

Of patients with available HCV population sequence data after failing to achieve SVR, a similar fraction of treatment-naive (T12/PR arm, ADVANCE) and treatment-experienced patients (Pooled TVR Arms, REALIZE) had resistance initially after failure. ‘After Failure’ indicates resistance profile at the visit representative of treatment failure. ‘End of Follow-up’ indicates the end of the follow-up observation period (end of study), with a median time of 12 months (range: 0 to 17 months) in ADVANCE and 9 months in REALIZE (range: 0 to 17 months).