Skip to main content
. 2012 Apr 12;7(4):e34971. doi: 10.1371/journal.pone.0034971

Figure 4. Pleural levels of CXCL12 and IL-5 after disruption of the CXCL12/CXCR4 axis.

Figure 4

CXCL12 (A) and IL-5 (B) expression levels measured by ELISA in pleural fluid of BALB/c mice and C57BL/6 mice 30 days post-inoculation and upon blockade either by chalcone (C04) or by AMD3100 (AMD) (days 10 and 20 p.i.). Results are presented after subtraction of the baseline production as mean ± SEM of 3 pooled independent experiments each carried out with 6 mice per group. The differences between strains and treatments were analysed by a two-way analysis of variance. Strain and treatment effects were significant for the pleural CXCL12 levels, and only the strain effect was significant for the pleural IL-5 level. Further comparisons were assessed by Bonferroni's multiple comparison test. “*” represents significant differences between treatments within one strain of mice (*p<0.05, **p<0.01); # shows significant differences between strains for one given treatment (###p<0.001).