Figure 7. D-Luciferin caused β-arrestin translocation via GPR35.
(a) The dose-dependent responses of three ligands as measured using Tango™ β-arrestin translocation gene reporter assays. (b) The dose-dependent responses of zaprinast in the presence of D-luciferin at different fixed doses. (c) The dose-dependent responses of D-luciferin in the presence of 10 µM zaprinast. All data were normalized to the zaprinast maximal response. The data represents mean ± s.d. from two independent measurements, each in duplicate (n = 4).
