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. 2012 Apr 12;7(4):e34588. doi: 10.1371/journal.pone.0034588

Table 4. Base Case Results for the Alternative Strategies for Cost, QALY Gained and ICER.

Cost ($) Utility (QALY) ICER
Cohort RT NT+RT TMZ+RT RT NT+RT TMZ+RT TMZ+RT VS. RT TMZ+RT VS. RT+NT NT+RT VS. RT
Overall cohort 7,234.0 8,655.9 32,562.4 0.80 0.84 1.09 87,940.6 94,968.3 39,185.1
Subgroups:
MGMT methylated 7,753.3 9,500.0 37,598.2 1.12 1.27 1.47 7,015.3 141,144.1 11,237.3
MGMT unmethylated 7,206.6 8,540.0 31,319.8 0.76 0.79 0.87 19,188.7 299,673.0 46,454.0
Complete resection 7,677.3 9,678.5 34,644.4 0.94 1.02 1.27 6,898.8 100,108.0 26,207.2
Partial resection 7,267.0 8,703.3 28,193.7 0.80 0.84 0.96 11,180.8 168,668.1 35,537.2
Biopsy only 6,074.1 6,855.1 25,598.8 0.57 0.61 0.73 10,741.1 157,802.5 23,883.3
Age <50 years 7,672.3 9,900.1 29,351.4 0.87 0.97 1.16 6,125.4 103,010.5 20,995.6
Age 50∼60 years 7,374.4 8,866.0 32,182.4 0.82 0.86 1.02 10,609.3 155,206.9 33,419.7
Age >60 years 6,990.5 8,261.0 26,388.8 0.78 0.79 0.86 21,434.9 279,507.5 120,317.5