Skip to main content
. 2012 Mar 2;18:565–573.

Table 2. Aqueous cytokine concentrations comparing TAU, IU, and Controls.

 
TAU n=10
IU n=15
Controls n=23
 
Cytokines Median Range (%) Mean±Std error Median Range (%) Mean±Std error Median Range (%) Mean±Std error Sensitivity
IL-2
3.4*
0–5 (9/10)
3.0±0.4
0.0‡
0–9 (2/15)
0.9±0.6
2.8
0–17 (17/23)
3.4±0.8
1.6
IFN-γ
26.3
0–219 (8/10)
66.9±24.5
10.9
0–71 (8/15)
17.3±5.9
12.7
0–91 (12/21)
15.6±4.5
6.4
IL-6
80.7†
2–2018 (7/9)
470.4±276.8
7.0‡
1–68 (11/13)
21.8±6.1
2.2
0–14 (8/22)
3.4±0.6
2.6
IL-10
1.9
0–4 (9/10)
2.0±0.4
0.3
0–8 (7/15)
1.3±0.6
1.5
0–5 (20/23)
1.7±0.2
0.3
IL-12
7.3*
2–15 (7/10)
7.1±1.4
0.0‡
0–2 (0/15)
0.5±0.2
8.7
0–27 (19/23)
8.7±1.3
3.5
TNF-α
12.1*
1–23 (8/10)
12.0±2.6
0.0‡
0–4 (0/14)
0.5±0.3
9.6
0–34 (17/23)
9.8±1.7
6.0
CCL2
380.8
158–1124 (10/10)
485.3±98.8
531.3‡
47–1354 (15/15)
604.7±113.9
180.9
32–962 (23/23)
252.5±50.5
1.1
CXCL8
61.7†
4–538 (10/10)
104.9±50.3
17.6‡
4–135 (15/15)
39.6±12.1
3.0
1–20 (21/22)
4.8±1.0
1.0
CXCL9
4790.6*†
81–51068 (9/9)
17115.9±6393.3
0.0
0–401 (5/11)
102.7±42.6
63.0
0–834 (19/21)
153.3±44.8
1.2
CXCL10
15621.1†
41–114173 (10/10)
49766.9±17640.0
631.6
0–107547 (11/15)
18632.6±9548.9
56.3
0–766 (20/22)
147.9±45.7
6.1
IL-9 8.26† 4–18 (9/9) 8.8±1.4 15.6‡ 0–45 (9/10) 16.5±4.0 5.5 0–11 (17/19) 5.5±0.6 2.5

TAU=uveitis associated with tuberculosis, IU: idiopathic uveitis; IFN-γ: interferon-gamma; TNF-α: tumor necrosis factor-alpha, CCL2: MCP-1, monocyte chemotactic protein-1; CXCL8 (IL-8, interleukin-8); CXCL9 (MIG, monokine induced by interferon-gamma); CXCL10 (IP-10, interferon-gamma-induced protein 10). Cytokines level at pg/ml. * p<0.05, for TAU versus IU; †p<0.05, for TAU versus controls; ‡ p<0.05, for IU versus controls by Mann-Whitney U test with Bonferroni correction.