Figure 5.
VEGF165b over-expression alters estrous cycling. Estrus cycle was determined in MMTV-VEGF165b transgenic mice, expressing VEGF165b in the ovary, and littermate sisters, by composition of cells in vaginal smears. Arrow, neutrophils; arrow head, parabasal cells; curved arrow, intermediate cells and *cornified superficial cells. (B) The TG mice had a significantly longer cycle time than the littermate controls. (C) Determination of the lengths of the cycles of each mice showed that estrus was longer by a day in the TG compared with WT mice. *P<0.05, Mann–Whitney U-test.