Table 1.

Inhibitory activities of aminomethanephosphonic and aminomethyl-P-methylphosphinic acid derivatives (NI not inhibitory)

No	Compound	Canavalia ensiformis urease		Bacillus pasteurii urease
		IC50 [μM]	K i [μM]	IC50 [μM]	K i [μM]
1		432 ± 37.8	240 ± 64.3	700 ± 23	314 ± 8.2
2		NI		1100 ± 10.5a	340 ± 22a
3		678 ± 48	204 ± 52	228 ± 15.6	70 ± 2,2
4		82 ± 26	21 ± 5.7	49 ± 1.7	13 ± 0.8
5		NI		NI
6		NI		300 ± 6.5	115 ± 7.4
7		NI		463 ± 34	148 ± 18.5
8		884 ± 14	224 ± 39	60.0 ± 0.3a	18.0 ± 0.7a
9		14.4 ± 4.8	3.7 ± 1.7	3.8 ± 0.4	0.62 ± 0.09
10		1 632 ± 226	571 ± 119	256 ± 12.8	72 ± 3.8
11		NI		NI
12		1 455 ± 189	295 ± 96	258 ± 12.7	95 ± 6.3

^aValues reported previously (Vassiliou 2008)