. 2012 Feb 5;21(4):1084–1093. doi: 10.1007/s10646-012-0861-z

Table 3.

Functional grouping of up- or down-regulated genes in Folsomia candida after 48 h exposure to 2-phenylethyl ITC in LUFA 2.2 soil at concentrations corresponding to the EC10 (6.21 nmol/g soil) and/or EC50 (10.7 nmol/g soil) for effects on reproduction compared to the acetone control

Process	Gene name	Blast2GO description	E-value	E-code	InterPro	EC10 logFC	EC50 logFC
Fatty acid metabolism
GO:0006633	Fcc00050^a	Acetyl-coenzyme a carboxylase alpha	3.32E-82	EC:6.4.1.2		0.961	1.086
GO:0006629	Fcc01007^a	Delta-5 fatty acid desaturase	7.10E-34		IPR005804	0.989
GO:0006633	Fcc02959^a	Fatty acid synthase	4.94E-23	EC:1.3.1.10	IPR000794	1.082	1.266
GO:0080090	Fcc00142	Sterol regulatory element-binding protein 1	1.43E-15				0.458
GO:0045540	Fcc06054^a	Sec14-like 2 (cerevisiae)	9.79E-09		IPR001251	0.693	0.594
	Fcc03602	Sec14-like 1 (cerevisiae)	1.85E-15		IPR001251	0.681
	Fcc04835	Sec14-like protein 4 (cral trio domain-containing protein)	1.44E-17		IPR001251	−1.184
	Fcc03980	Diacylglycerol o-acyltransferase	2.44E-09			−1.554
	Fcc03847	Alkaline ceramidase	2.66E-16			0.643
Oxidative stress
GO:0005515	Fcc00494^a	Glutathione s-transferase	7.64E-39		IPR004045	0.703	0.830
GO:0005515	Fcc05973^a	Glutathione s-transferase	1.48E-42		IPR004045		1.123
GO:0055114	Fcc02155^a	Cytochrome p450	2.84E-32		IPR001128		1.002
GO:0005215	Fcc04663^a	Alpha-tocopherol transfer	4.36E-42		IPR001071		−0.746
GO:0006979	Fcc00022^a	Rec8	1.54E-20		IPR002007		−1.150
Immune response
GO:0009058	Fcc00057^a	Isopenicillin n synthetase	2.16E-29				0.856
GO:0006950	Fcc03623^a	Advillin	2.71E-47		IPR003128	0.604	0.596
Sugar metabolism
GO:0003824	Fcc05611^a	Trehalase	2.51E-46		IPR001661		0.868
GO:0050660	Fcc04789^a	Glucose dehydrogenase	1.54E-15		IPR007867		0.827
GO:0006565	Fcc02499^a	Cystathionine beta-synthase	5.25E-61	EC:4.2.1.22			0.788
GO:0009744	Fcc00529^a	Maltase- intestinal-like	8.26E-30	EC:3.2.1.26	IPR000322	1.188	1.309
GO:0015986	Fcc03280^a	Vacuolar atpase subunit d	5.11E-71	EC:3.6.3.6	IPR002699		−0.582
Growth and development
GO:0005214	Fcc03188^a	Adult cuticle	3.21E-17		IPR000618		−0.801
GO:0005576	Fcc04617^b	Follistatin precursor	6.66E-29		IPR001239		−1.351
	Fcc00558	Chitin binding peritrophin-	4.14E-07			0.595
GO:0006032	Fcc02522^a	Endochitinase	1.33E-29		IPR000726	1.110	1.080
GO:0006032	Fcc00881^a	Acidic mammalian chitinase-like	1.40E-51	EC:3.2.1.0	IPR001223	1.124	0.889
GO:0008152	Fcc03673^a	Juvenile hormone acid methyltransferase	2.34E-23	EC:2.1.1.0	IPR013216	0.794	1.034
Transcription
GO:0043967	Fcc03584^a	Dna methyltransferase 1 associated protein 1	9.69E-71				−0.518
GO:0003899	Fcc04065^a	Dna-directed rna polymerase ii subunit rpb4	1.61E-51	EC:2.7.7.6	IPR005574		−0.716

Bold indicate up-regulation of genes while italic indicate down-regulation of genes. Empty cells indicate the gene was not differentially expressed compared to the acetone control

Process Biological process category and related GO-code of gene (if available), GeneName Collembase accession number, Blast Description Best Blast2GO hit, E-value Blast2GO E-value, E-Code Enzyme Commission number, InterPro first code of hits found in InterPro database, logFC the log2 transformed ratio (treated/untreated)

^a Sequence was fully annotaded by Blast2GO

^b Second best annotated Blast2GO description for this sequence