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. 2012 Apr 14;18(14):1664–1671. doi: 10.3748/wjg.v18.i14.1664

Table 2.

Expressions of 5 molecular markers in gastric and small intestinal gastrointestinal stromal tumor

Protein Gastric GISTs Small intestinal GISTs
Positive (%) P value Positive (%) P value
DOD (n = 13) Alive (n = 48) DOD (n = 15) Alive (n = 27)
CD44s 5 (38.4) 35 (72.9) 0.020 15 (100) 23 (85.2) 0.397
MMP-9 11 (84.6) 23 (47.9) 0.018 11 (73.3) 22 (81.5) 0.339
TIMP-1 7 (53.8) 22 (45.8) 0.608 3 (20.0) 14 (51.9) 0.085
PTEN
< 50% 5 (38.5) 8 (8.3) 0.014 11 (73.3) 6 (22.2) 0.003
≥ 50% 8 (61.5) 44 (91.7) 4 (26.7) 21 (77.8)
Ki-67
< 5% 7 (53.8) 41 (85.4) 0.022 5 (33.3) 24 (88.9) 0.0001
≥ 5% 6 (46.2) 7 (14.6) 10 (66.7) 3 (11.1)

GIST: Gastrointestinal stromal tumor; MMP: Matrix metalloproteinase.